MLB Predictions - MLBGameSim.com

MLB Predictions for 5/22/2025


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Odds: Line |  O/U |  Money Line
Time *ETMatchupPredictionActualResult
12:35 PM Texas Rangers @ New York Yankees  
Nathan Eovaldi vs Carlos Rodon
by 1.5
+/- Lineups
New York Yankees win 3.0-2.0
  by 1.0
New York Yankees wins 1-0
  
1:07 PM San Diego Padres @ Toronto Blue Jays  
Stephen Kolek vs Bowden Francis
by 1.5
+/- Lineups
San Diego Padres win 5.1-4.0
  by 1.1
Toronto Blue Jays wins 7-6
 
3:10 PM Philadelphia Phillies @ Colorado Rockies  
Ranger Suarez vs German Marquez
by 1.5
+/- Lineups
Philadelphia Phillies win 5.2-3.7
  by 1.5
Philadelphia Phillies wins 2-0
  
3:35 PM Los Angeles Angels @ Athletics  
Tyler Anderson vs Luis Severino
by 1.5
+/- Lineups
Athletics win 3.9-3.5
  by 0.4
Los Angeles Angels wins 10-5
 
6:40 PM Milwaukee Brewers @ Pittsburgh Pirates  
Aaron Civale vs Mike Burrows
by 1.5
+/- Lineups
Milwaukee Brewers win 4.1-3.8
  by 0.3
Milwaukee Brewers wins 8-5
6:40 PM Cleveland Guardians @ Detroit Tigers  
Tanner Bibee vs Jack Flaherty
by 1.5
+/- Lineups
Detroit Tigers win 5.4-4.2
  by 1.1
Cleveland Guardians wins 7-0
 
6:45 PM Baltimore Orioles @ Boston Red Sox  
Cade Povich vs Lucas Giolito
by 1.5
Simulate
Postponed
 
6:45 PM Atlanta Braves @ Washington Nationals  
AJ Smith-Shawver vs Trevor Williams
by 1.5
+/- Lineups
Atlanta Braves win 4.6-3.9
  by 0.6
Washington Nationals wins 8-7
 
8:10 PM Seattle Mariners @ Houston Astros  
George Kirby vs Lance McCullers
by 1.5
+/- Lineups
Seattle Mariners win 4.6-3.5
  by 1.1
Houston Astros wins 9-2
 

Legend/Totals

Correct Picks 3 (37.5%)
Incorrect Picks 5 (62.5%)
Final Margin within 5 Pts 2 (25.0%)
Beat the Spread 7 (87.5%)
         
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