MLB Predictions - MLBGameSim.com

MLB Predictions for 6/5/2025


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Odds: Line |  O/U |  Money Line
Time *ETMatchupPredictionActualResult
12:15 PM Arizona Diamondbacks @ Atlanta Braves  
Brandon Pfaadt vs Grant Holmes
-154 or 60.6%
+/- Lineups
Atlanta Braves win 55.4% of sims
  by 0.2
Arizona Diamondbacks wins 11-10
 
1:45 PM Kansas City Royals @ St. Louis Cardinals  
Noah Cameron vs Miles Mikolas
-115 or 53.5%
+/- Lineups
St. Louis Cardinals win 50.1% of sims
  by 0.2
St. Louis Cardinals wins 6-5
2:10 PM Detroit Tigers @ Chicago White Sox  
Casey Mize vs Sean Burke
-172 or 63.2%
+/- Lineups
Chicago White Sox win 50.6% of sims
  by 0.2
Chicago White Sox wins 3-2
 
3:07 PM Philadelphia Phillies @ Toronto Blue Jays  
Jesus Luzardo vs Chris Bassitt
-102 or 50.5%
+/- Lineups
Toronto Blue Jays win 52.8% of sims
  by 0.2
Toronto Blue Jays wins 9-1
 
3:35 PM Minnesota Twins @ Athletics  
David Festa vs Mitch Spence
-160 or 61.5%
+/- Lineups
Minnesota Twins win 54.1% of sims
  by 0.7
Athletics wins 14-3
 
3:40 PM Baltimore Orioles @ Seattle Mariners  
Zach Eflin vs Bryan Woo
-155 or 60.8%
+/- Lineups
Seattle Mariners win 62.7% of sims
  by 1.0
Baltimore Orioles wins 4-3
3:45 PM San Diego Padres @ San Francisco Giants  
Dylan Cease vs Robbie Ray
-115 or 53.5%
+/- Lineups
San Francisco Giants win 54.3% of sims
  by 0.3
San Francisco Giants wins 3-2
  
4:10 PM New York Mets @ Los Angeles Dodgers  
David Peterson vs Landon Knack
-131 or 56.7%
+/- Lineups
Los Angeles Dodgers win 59.5% of sims
  by 0.7
Los Angeles Dodgers wins 6-5
  
6:40 PM Houston Astros @ Pittsburgh Pirates  
Framber Valdez vs Mitch Keller
-120 or 54.5%
+/- Lineups
Houston Astros win 63.9% of sims
  by 1.5
Houston Astros wins 8-2
 
6:45 PM Chicago Cubs @ Washington Nationals  
Colin Rea vs Jake Irvin
-127 or 55.9%
+/- Lineups
Washington Nationals win 55.5% of sims
  by 0.5
Chicago Cubs wins 7-1
7:05 PM Cleveland Guardians @ New York Yankees  
Slade Cecconi vs Max Fried
-275 or 73.3%
+/- Lineups
New York Yankees win 77.4% of sims
  by 2.9
New York Yankees wins 4-0
 
7:35 PM Texas Rangers @ Tampa Bay Rays  
Jack Leiter vs Ryan Pepiot
-142 or 58.7%
+/- Lineups
Tampa Bay Rays win 51.0% of sims
  by 0.1
Tampa Bay Rays wins 4-3
7:45 PM Kansas City Royals @ St. Louis Cardinals  
Cole Ragans vs Matthew Liberatore
-115 or 53.5%
+/- Lineups
St. Louis Cardinals win 63.9% of sims
  by 1.2
Kansas City Royals wins 7-5

Legend/Totals

Correct Picks 4 (30.8%)
Incorrect Picks 9 (69.2%)
Final Margin within 5 Pts 2 (15.4%)
Beat the Spread 8 (61.5%)
         
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