MLB Predictions - MLBGameSim.com

MLB Predictions for 9/25/2021


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Odds: Line |  O/U |  Money Line
Time *ETMatchupPredictionActualResult
2:20 PM St. Louis Cardinals @ Chicago Cubs  
Jon Lester vs Adrian Sampson
-128 or 56.1%
Chicago Cubs win 53.5% of sims
  by 0.1
St. Louis Cardinals wins 8-5
4:05 PM Pittsburgh Pirates @ Philadelphia Phillies  
Wil Crowe vs Ranger Suarez
-293 or 74.6%
Philadelphia Phillies win 72.3% of sims
  by 1.8
Philadelphia Phillies wins 3-0
4:07 PM Houston Astros @ Athletics  
Framber Valdez vs Sean Manaea
-102 or 50.5%
Houston Astros win 54.1% of sims
  by 0.7
Athletics wins 2-1
4:10 PM New York Yankees @ Boston Red Sox  
Nestor Cortes vs Nick Pivetta
-110 or 52.4%
Boston Red Sox win 52.4% of sims
  by 0.0
New York Yankees wins 5-3
6:10 PM Kansas City Royals @ Detroit Tigers  
Jon Heasley vs Tarik Skubal
-130 or 56.5%
Kansas City Royals win 55.4% of sims
  by 0.8
Detroit Tigers wins 5-1
6:10 PM Miami Marlins @ Tampa Bay Rays  
Sandy Alcantara vs Shane McClanahan
-198 or 66.4%
Tampa Bay Rays win 50.1% of sims
  by 0.1
Tampa Bay Rays wins 7-3
7:05 PM Texas Rangers @ Baltimore Orioles  
Jordan Lyles vs Chris Ellis
-108 or 51.9%
Baltimore Orioles win 58.0% of sims
  by 0.6
Baltimore Orioles wins 3-2
  
7:10 PM Washington Nationals @ Cincinnati Reds  
Erick Fedde vs Vladimir Gutierrez
-126 or 55.8%
Cincinnati Reds win 64.5% of sims
  by 1.4
Cincinnati Reds wins 7-6
  
7:10 PM Toronto Blue Jays @ Minnesota Twins  
Robbie Ray vs John Gant
-155 or 60.8%
Toronto Blue Jays win 52.6% of sims
  by 0.4
Toronto Blue Jays wins 6-1
7:10 PM New York Mets @ Milwaukee Brewers  
Rich Hill vs Corbin Burnes
-215 or 68.3%
Milwaukee Brewers win 63.9% of sims
  by 1.2
Milwaukee Brewers wins 2-1
 
7:15 PM Atlanta Braves @ San Diego Padres  
Huascar Ynoa vs Vince Velasquez
-105 or 51.2%
Atlanta Braves win 62.7% of sims
  by 1.1
Atlanta Braves wins 10-8
  
7:15 PM Chicago White Sox @ Cleveland Guardians  
Lance Lynn vs Eli Morgan
-160 or 61.5%
Chicago White Sox win 62.3% of sims
  by 1.4
Cleveland Guardians wins 6-0
8:10 PM Los Angeles Dodgers @ Arizona Diamondbacks  
Clayton Kershaw vs Zac Gallen
-220 or 68.8%
Los Angeles Dodgers win 56.2% of sims
  by 0.7
Arizona Diamondbacks wins 7-2
 
8:10 PM San Francisco Giants @ Colorado Rockies  
Anthony DeSclafani vs Jon Gray
-121 or 54.8%
San Francisco Giants win 58.0% of sims
  by 0.8
San Francisco Giants wins 7-2
 
9:07 PM Seattle Mariners @ Los Angeles Angels  
Tyler Anderson vs Jaime Barria
-120 or 54.5%
Seattle Mariners win 57.0% of sims
  by 1.1
Los Angeles Angels wins 14-1

Legend/Totals

Correct Picks 9 (60.0%)
Incorrect Picks 6 (40.0%)
Final Margin within 5 Pts 4 (26.7%)
Beat the Spread 5 (33.3%)
         
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