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The NFL schedule for December 28, 2025, brings a trio of tantalizing matchups that could shake up the playoff picture. Whether you're a fan or a bettor, these games offer plenty of drama and potential for surprises. Let's dive into the head-to-heads that are set to keep us on the edge of our seats.
Leading off, we have the Arizona Cardinals taking on the Cincinnati Bengals in what promises to be an aerial showdown. Jacoby Brissett and Joe Burrow will command center stage, each looking to exploit the other's secondary. Our GameSim model gives a slight nod to the Bengals, with a predicted scoreline of 28.6-27.4 and a 52% win probability for Cincinnati. Burrow is expected to throw for over 300 yards and nearly three touchdowns, making him a must-watch in this high-stakes encounter.
But don't count out Brissett, who is projected for an impressive 321 passing yards and 2.6 touchdowns. This game could hinge on which quarterback can maintain composure under pressure. With both offenses likely to light up the scoreboard, the over/under of 53.5 seems within reach.
Next up, the Pittsburgh Steelers head to Cleveland, where the Browns are slight favorites with a predicted 23.5-21.3 victory. This matchup is a classic AFC North battle, featuring Pittsburgh's seasoned Aaron Rodgers against the up-and-coming Shedeur Sanders of the Browns. According to our simulations, both quarterbacks are expected to throw for nearly identical yardage and touchdowns, making this a potentially tight contest.
The key might lie in the rushing game, where Jaylen Warren and Kenneth Gainwell will look to break through a stout Browns defense. With a lower over/under set at 34.5, expect a grind-it-out style game that could swing on a single big play or crucial turnover.
Rounding out the day's action, the New Orleans Saints are poised to edge out the Tennessee Titans, with a predicted score of 21.3-20.7. Despite the close odds, the Saints hold a slight edge according to our projections. Tyler Shough's performance under center will be crucial, as he's expected to accumulate nearly 270 yards and close to two touchdowns.
On the Titans' side, Cam Ward and Tony Pollard will aim to keep the chains moving. Pollard, with a projected 71.8 rushing yards, will be pivotal in controlling the tempo for Tennessee. As both teams vie for playoff positioning, this matchup could have significant implications for the postseason landscape.
With playoff hopes hanging in the balance, each of these games is packed with storylines and pivotal player performances. For those looking to dive deeper into the stats and projections, GameSim+ subscribers get access to detailed player stats and insights. Learn more about GameSim+ and how it can enhance your game day experience.
